Data Sciences International (DSI) is excited to announce the first expansion to its SoHo Implantable Telemetry platform, released in 2024, enabling measurement of biopotentials (e.g. EEG, EMG, ECG) in small laboratory animals. Transform your studies with this advanced implantable telemetry system designed to break free from traditional constraints with the quality you trust. The SoHo telemetry system empowers you to design and execute studies on your terms.

Technical Innovation Meets Research Precision

The SoHo Telemetry system redefines research capabilities by delivering an unprecedented combination of ease, reliability, and scientific integrity. Designed with researchers' most critical needs in mind, this innovative platform transforms data collection from a complex challenge to a streamlined, powerful research tool. Researchers can now capture continuous, high-quality physiological data from freely moving animals within their social groups, all while minimizing experimental stress and maximizing scientific insights.

Versatility to Inspire Innovation

Ignite innovation with a versatile system designed to fuel creativity and adapt to your evolving research needs. SoHo seamlessly integrates physiological monitoring in high-density setups, such as ventilated racks and environmental chambers, while also supporting behavioral endpoints like mazes, treadmills, and behavioral boxes. Optimized for extra-small to medium-sized animal models, it empowers researchers to push boundaries, gain deeper insights, and achieve breakthroughs.

Efficient Design, Unmatched Convenience

Streamline your research with user-controlled implant power management to extend battery life and operate on your terms. Remote power management, real-time status notifications, and extended transmission range minimize physical interactions, reducing stress artifacts while enhancing animal welfare and researcher safety. Combined with a compact system design that maximizes lab space, this solution accelerates your workflow, making it faster, safer, and more effective.

Advancing the 3Rs for Ethical Research

Promote animal welfare with a system that reduces stress, supports social housing, and minimizes the number of animals required per study—all while adhering to the highest ethical and regulatory standards.

Backed by the Trusted Ponemah Software

With over 3400 licenses sold, countless studies supported, and comprehensive reporting for regulatory approval, Ponemah software is the backbone of DSI’s physiological monitoring platform, including SoHo. With Ponemah and SoHo, you can confidently collect, accurately analyze, and quickly summarize your telemetry data so you can focus on what really matters, the science! 

Comprehensive Data with Numerous Applications

EEG + EMG: Analyze Neurological and Cognitive Conditions

• Real-time brain activity monitoring in longitudinal studies with the same subject, allowing for quantification of behavioral and physiological change over time.

• Diagnosis of neurological disorders, including epilepsy, sleep, and brain tumors.
• Cognitive and behavioral studies, including attention, memory, and decision-making.

• Emotional and stress responses for mental health conditions, including anxiety and depression.

ECG: Evaluate Cardiovascular Function

• Monitoring heart rate and rhythm to detect arrhythmia, ischemia, and other cardiac conditions.
• Analyzing variations in heart rate variability (HRV) to assess autonomic nervous system function and its impact on cardiovascular health.
• Heart rate and ECG are used as biomarkers of ischemia and myocardial infarction (MI).

Core Body Temperature + Locomotor Activity: Assess Thermoregulation and Changes in Activity Levels

• Critical to circadian rhythm and infectious disease studies including onset and trigger to treat.
• Confidently acquire real-time data from challenging Biological Safety Level (BSL) environments.
• Accurate temperature measures over a wide range for hibernation studies.
• Precise movement detection via 3 axis accelerometer environments with a small hardware footprint.

Combined Applications

• Integrate with behavioral and metabolic equipment to study the connection between physiological and behavioral responses in various disease models; valuable for research in areas such as sleep, stress, anxiety, learning, memory, social interaction, drug effects, pain, neurological disorders, and exercise.
• Add telemetry to respiratory solutions to investigate the link between cardiovascular or neurological function and respiratory function in studies on cardiovascular interactions, sleep apnea, neural control of breathing, and stress or anxiety.

Looking Ahead

DSI has been serving researchers for over 40 years with many first-of-their-kind innovations and is excited to continue pushing the boundaries of what’s possible in preclinical research. Stay tuned for more innovations and stories of how this technology is changing the game.

Let’s chat! 

Are you looking for solutions to enhance your physiological research? Contact DSI today, and our team will connect with you!